BDBM179867 US11147820, Compound Metopimazine::US9132134, Metopimazine (NG101)

SMILES CS(=O)(=O)c1ccc2Sc3ccccc3N(CCCN3CCC(CC3)C(O)=N)c2c1

InChI Key InChIKey=BQDBKDMTIJBJLA-UHFFFAOYSA-N

Data  8 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 179867   

TargetD(3) dopamine receptor(Homo sapiens (Human))
Neurogastrx

US Patent
LigandPNGBDBM179867(US11147820, Compound Metopimazine | US9132134, Met...)
Affinity DataKi:  0.610nMAssay Description:The pharmacological profile of metopimazine, metopimazine acid (MPZA), domperidone, and metoclopramide were assessed by radioligand binding and by a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Neurogastrx

US Patent
LigandPNGBDBM179867(US11147820, Compound Metopimazine | US9132134, Met...)
Affinity DataKi:  0.610nMAssay Description:For the radioligand binding assay, cell membranes of dopamine D2 receptor expressing cells were incubated with [3H]spiperone and competing drugs in b...More data for this Ligand-Target Pair
In DepthDetails US Patent